Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Good
Based on 4 Reviews
8.5
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Folate
1,360 mcg DFE** (800 mcg folic acid)
340%
Vitamin B-12 (as Cyanocobalamin)
25 mcg
1042%
Top Medical Research Studies
7
We explored the relationship between folate intake and knee pain in patients suffering from knee osteoarthritis (OA) over a two-year period. In this insightful study, data was collected from participants enrolled in a rigorous clinical trial designed to assess the effects of vitamin D supplementation. While the original trial focused on vitamin D, our post-hoc analysis allowed us to dive into the potential benefits of folate on knee pain and related conditions.
Through the use of dietary questionnaires, we assessed the average daily folate consumption of participants. In addition to evaluating knee pain levels at various intervals, other factors such as inflammatory markers, muscle strength, and comorbidities were also monitored. Impressively, we found that increased folate intake was associated with reduced knee pain and lower levels of inflammatory substances known as adipokines.
Furthermore, individuals with higher folate consumption reported fewer comorbid conditions, suggesting that folate may indeed play a role in enhancing overall health for those dealing with knee OA. However, while our findings are promising, they highlight the need for further research to fully understand the extent of folate's impact in this context.
Through the use of dietary questionnaires, we assessed the average daily folate consumption of participants. In addition to evaluating knee pain levels at various intervals, other factors such as inflammatory markers, muscle strength, and comorbidities were also monitored. Impressively, we found that increased folate intake was associated with reduced knee pain and lower levels of inflammatory substances known as adipokines.
Furthermore, individuals with higher folate consumption reported fewer comorbid conditions, suggesting that folate may indeed play a role in enhancing overall health for those dealing with knee OA. However, while our findings are promising, they highlight the need for further research to fully understand the extent of folate's impact in this context.
Most Useful Reviews
9
Pain-free menstruation
I have been taking folic acid for two months. The most significant effect for me was pain-free menstruation, which started five days earlier than expected. Along with this, there’s no fatigue or moodiness. Folic acid also positively influences emotional well-being and reduces PMS symptoms, and it has no side effects, apart from rare individual intolerance. I highly recommend this supplement; it’s beneficial for every woman.
9
Improved health
Folic acid is wonderful. I have menopause, and my doctor advised me to take it. I felt better, look younger, severe sweating ceased, and the pain in my lower abdomen stopped. I hope this comment helps someone. Thank you!
7.5
Vital vitamins
These vitamins are excellent for women's health and cancer prevention, as recommended by my doctor. Only one tablet a day is needed, making it convenient and economical. After taking them, my cycle normalised and the knee pain during PMS almost vanished. Additionally, drowsiness and irritability faded, and the quality of my nails and hair improved. I follow a four-week course with breaks. I prefer ordering from here as prices in Moscow pharmacies are extremely high.
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
- All Researches
7
We explored the relationship between folate intake and knee pain in patients suffering from knee osteoarthritis (OA) over a two-year period. In this insightful study, data was collected from participants enrolled in a rigorous clinical trial designed to assess the effects of vitamin D supplementation. While the original trial focused on vitamin D, our post-hoc analysis allowed us to dive into the potential benefits of folate on knee pain and related conditions.
Through the use of dietary questionnaires, we assessed the average daily folate consumption of participants. In addition to evaluating knee pain levels at various intervals, other factors such as inflammatory markers, muscle strength, and comorbidities were also monitored. Impressively, we found that increased folate intake was associated with reduced knee pain and lower levels of inflammatory substances known as adipokines.
Furthermore, individuals with higher folate consumption reported fewer comorbid conditions, suggesting that folate may indeed play a role in enhancing overall health for those dealing with knee OA. However, while our findings are promising, they highlight the need for further research to fully understand the extent of folate's impact in this context.
Through the use of dietary questionnaires, we assessed the average daily folate consumption of participants. In addition to evaluating knee pain levels at various intervals, other factors such as inflammatory markers, muscle strength, and comorbidities were also monitored. Impressively, we found that increased folate intake was associated with reduced knee pain and lower levels of inflammatory substances known as adipokines.
Furthermore, individuals with higher folate consumption reported fewer comorbid conditions, suggesting that folate may indeed play a role in enhancing overall health for those dealing with knee OA. However, while our findings are promising, they highlight the need for further research to fully understand the extent of folate's impact in this context.
User Reviews
USERS' SCORE
Good
Based on 4 Reviews
8.5
- All Reviews
- Positive Reviews
- Negative Reviews
9
Pain-free menstruation
I have been taking folic acid for two months. The most significant effect for me was pain-free menstruation, which started five days earlier than expected. Along with this, there’s no fatigue or moodiness. Folic acid also positively influences emotional well-being and reduces PMS symptoms, and it has no side effects, apart from rare individual intolerance. I highly recommend this supplement; it’s beneficial for every woman.
9
Improved health
Folic acid is wonderful. I have menopause, and my doctor advised me to take it. I felt better, look younger, severe sweating ceased, and the pain in my lower abdomen stopped. I hope this comment helps someone. Thank you!
7.5
Vital vitamins
These vitamins are excellent for women's health and cancer prevention, as recommended by my doctor. Only one tablet a day is needed, making it convenient and economical. After taking them, my cycle normalised and the knee pain during PMS almost vanished. Additionally, drowsiness and irritability faded, and the quality of my nails and hair improved. I follow a four-week course with breaks. I prefer ordering from here as prices in Moscow pharmacies are extremely high.
9
Remarkable results
I will share my colleague's experience. She always endured severe knee pain during the first days of her cycle. After taking these vitamins, she experienced her first day without pain! I was shocked by her story. Folic acid is essential for women, especially when combined with vitamin B12!
Frequently Asked Questions
7.5
Vital vitamins
These vitamins are excellent for women's health and cancer prevention, as recommended by my doctor. Only one tablet a day is needed, making it convenient and economical. After taking them, my cycle normalised and the knee pain during PMS almost vanished. Additionally, drowsiness and irritability faded, and the quality of my nails and hair improved. I follow a four-week course with breaks. I prefer ordering from here as prices in Moscow pharmacies are extremely high.
9
Remarkable results
I will share my colleague's experience. She always endured severe knee pain during the first days of her cycle. After taking these vitamins, she experienced her first day without pain! I was shocked by her story. Folic acid is essential for women, especially when combined with vitamin B12!
9
Pain-free menstruation
I have been taking folic acid for two months. The most significant effect for me was pain-free menstruation, which started five days earlier than expected. Along with this, there’s no fatigue or moodiness. Folic acid also positively influences emotional well-being and reduces PMS symptoms, and it has no side effects, apart from rare individual intolerance. I highly recommend this supplement; it’s beneficial for every woman.
9
Improved health
Folic acid is wonderful. I have menopause, and my doctor advised me to take it. I felt better, look younger, severe sweating ceased, and the pain in my lower abdomen stopped. I hope this comment helps someone. Thank you!
7
We explored the relationship between folate intake and knee pain in patients suffering from knee osteoarthritis (OA) over a two-year period. In this insightful study, data was collected from participants enrolled in a rigorous clinical trial designed to assess the effects of vitamin D supplementation. While the original trial focused on vitamin D, our post-hoc analysis allowed us to dive into the potential benefits of folate on knee pain and related conditions.
Through the use of dietary questionnaires, we assessed the average daily folate consumption of participants. In addition to evaluating knee pain levels at various intervals, other factors such as inflammatory markers, muscle strength, and comorbidities were also monitored. Impressively, we found that increased folate intake was associated with reduced knee pain and lower levels of inflammatory substances known as adipokines.
Furthermore, individuals with higher folate consumption reported fewer comorbid conditions, suggesting that folate may indeed play a role in enhancing overall health for those dealing with knee OA. However, while our findings are promising, they highlight the need for further research to fully understand the extent of folate's impact in this context.
Through the use of dietary questionnaires, we assessed the average daily folate consumption of participants. In addition to evaluating knee pain levels at various intervals, other factors such as inflammatory markers, muscle strength, and comorbidities were also monitored. Impressively, we found that increased folate intake was associated with reduced knee pain and lower levels of inflammatory substances known as adipokines.
Furthermore, individuals with higher folate consumption reported fewer comorbid conditions, suggesting that folate may indeed play a role in enhancing overall health for those dealing with knee OA. However, while our findings are promising, they highlight the need for further research to fully understand the extent of folate's impact in this context.
References
- Liu Z, Chen Z, Wu Z, Tang M, Lin Y, et al. Associations between folate intake and knee pain, inflammation mediators and comorbid conditions in patients with symptomatic knee osteoarthritis. BMC Musculoskelet Disord. 2024;25:973. doi:10.1186/s12891-024-08095-5
